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Clinical Effectiveness of Percutaneous Auricular Vagus Nerve Stimulation in Chronic Back Pain Patients – A Single-Centre Retrospective Analysis

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Clinical Effectiveness of Percutaneous Auricular Vagus Nerve Stimulation in Chronic Back Pain Patients – A Single-Centre Retrospective Analysis

Ann Pain Med
Volume 3, Issue 1
Author
Jozsef Constantin Széles , Stefan Kampusch , Van Hoang Le , David Philipp Enajat , Eugenijus Kaniusas and Christoph Neumayer
Author Information

1Department of General Surgery, Division of Vascular Surgery, Medical University of Vienna, Austria

2Institute of Electrodynamics, Microwave and Circuit Engineering, Vienna University of Technology, Austria

3SzeleSTIM GmbH, Austria

Correspondance to: Jozsef Constantin Széles
Abstract
Objectives
Chronic back pain is one of the biggest causes of disability today. The objective of this study was to evaluate the safety and effectiveness of percutaneous auricular Vagus Nerve Stimulation (pVNS) for chronic back pain patients in routine clinical practice.
Methods
Data were retrospectively sourced from a clinical database. Mean reduction in average and maximum pain intensity at three weeks as compared to baseline using Numeric Rating Scale (NRS) pain intensity was assessed. A patient responder was defined as having at least 50% improvement in average NRS pain intensity, assessed at 1-, 3- and 6-weeks, as well as 3 months. In addition, analgesic intake, subjective well-being and number and type of Adverse Events (AEs) were reported.
Results

A total of 148 patients underwent pVNS stimulation and met all inclusion criteria. Average NRS pain intensity significantly decreased from 6.36 ± 2.18 at baseline to 3.25 ± 1.83 (p<0.001) at three weeks of treatment. One week into treatment, the responder rate was 32.4%, while reaching a maximum of 58.8% at six weeks of treatment. 60% of patients taking opioid analgesics at baseline were able to decrease or stop their opioid usage. Reported AEs were mild and pVNS was welltolerated.

Discussion
Our results suggest that pVNS may be a safe and effective adjunct treatment for difficult to treat chronic back pain patients. Given the retrospective nature of this study, further research is warranted to confirm these findings.
Keywords:
Citation:
Széles JC, Kampusch S, Le VH, Enajat DP, Kaniusas E, Neumayer C. Clinical Effectiveness of Percutaneous Auricular Vagus Nerve Stimulation in Chronic Back Pain Patients – A Single-Centre Retrospective Analysis. Annals Pain Med. 2021;3(1):1009..
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