Generated by All in One SEO v4.9.5.1, this is an llms.txt file, used by LLMs to index the site. # Neuro Care USA ## Sitemaps - [XML Sitemap](http://neurocareusa.com/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Extracorporeal shock wave therapy effectively prevented diabetic neuropathy](http://neurocareusa.com/extracorporeal-shock-wave-therapy-effectively-prevented-diabetic-neuropathy/) - We tested the hypothesis that extracorporeal shock wave (ECSW) therapy can effectively protect sciatic nerve (SN) from diabetes mellitus (DM)-induced neuropathy in leptin-deficient (ob/ob) mice. - [Treatment of Peripheral Neuropathy: Combination Therapy Using LED Light, Extracorporeal Shockwave Therapy, Platelet Rich Plasma, and an Oral Dietary Supplement](http://neurocareusa.com/treatment-of-peripheral-neuropathy-combination-therapy-using-led-light-extracorporeal-shockwave-therapy-platelet-rich-plasma-and-an-oral-dietary-supplement/) - Peripheral neuropathy (PN) is a significant contributor to disability in the elderly. It is also one of the most prevalent complications of type 2 diabetes, prediabetes and metabolic syndrome. - [Effect of Treatment of Neuropathic and Ischemic Diabetic Foot Ulcers with the Use of Local Ozone Therapy Procedures—An Observational Single Center Study](http://neurocareusa.com/effect-of-treatment-of-neuropathic-and-ischemic-diabetic-foot-ulcers-with-the-use-of-local-ozone-therapy-procedures-an-observational-single-center-study/) - Diabetes ranks high among worldwide global health problems, and diabetic foot ulcer syndrome (DFU) is considered as one of its most serious complications. - [Case Report: Successful Outcome for Refractory Diabetic Peripheral Neuropathy in Patients With Ultrasound-Guided Injection Treatment](http://neurocareusa.com/case-report-successful-outcome-for-refractory-diabetic-peripheral-neuropathy-in-patients-with-ultrasound-guided-injection-treatment/) - Diabetic peripheral neuropathy is the most prevalent chronic complication of diabetes and is based on sensory and autonomic nerve symptoms. - [Effectiveness of platelet rich plasma (PRP) treatment and its comparison with pregabalin in painful diabetic polyneuropathy: A randomized controlled clinical trial](http://neurocareusa.com/effectiveness-of-platelet-rich-plasma-prp-treatment-and-its-comparison-with-pregabalin-in-painful-diabetic-polyneuropathy-a-randomized-controlled-clinical-trial/) - The most common consequence of diabetes mellitus (DM) is diabetic peripheral neuropathy (DPN), and it has serious clinical implications that can affect patients' quality of life. - [Neuromuscular electrical stimulation in critically ill traumatic brain injury patients attenuates muscle atrophy, neurophysiological disorders, and weakness: a randomized controlled trial](http://neurocareusa.com/neuromuscular-electrical-stimulation-in-critically-ill-traumatic-brain-injury-patients-attenuates-muscle-atrophy-neurophysiological-disorders-and-weakness-a-randomized-controlled-trial/) - Critically ill traumatic brain injury (TBI) patients experience extensive muscle damage during their stay in the intensive care unit. - [Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis](http://neurocareusa.com/vagus-nerve-stimulation-inhibits-cytokine-production-and-attenuates-disease-severity-in-rheumatoid-arthritis/) - Rheumatoid arthritis (RA) is a heterogeneous, prevalent, chronic autoimmune disease characterized by painful swollen joints and significant disabilities. - [Percutaneous Auricular Vagus Nerve Stimulation Reduces Inflammation in Critical Covid-19 Patients](http://neurocareusa.com/percutaneous-auricular-vagus-nerve-stimulation-reduces-inflammation-in-critical-covid-19-patients/) - Covid-19 is an infectious disease associated with cytokine storms and derailed sympatho-vagal balance leading to respiratory distress, hypoxemia and cardiovascular damage. - [Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis](http://neurocareusa.com/non-invasive-neuromodulation-effects-on-painful-diabetic-peripheral-neuropathy-a-systematic-review-and-meta-analysis/) - Diabetic Peripheral Neuropathy (DPN) typically is accompanied by painful symptoms. Several therapeutic agents have been tried for symptomatic relief, but with varying results. - [Evoked pain analgesia in chronic pelvic pain patients using respiratory-gated auricular vagal afferent nerve stimulation](http://neurocareusa.com/evoked-pain-analgesia-in-chronic-pelvic-pain-patients-using-respiratory-gated-auricular-vagal-afferent-nerve-stimulation/) - Previous vagus nerve stimulation (VNS) studies have demonstrated antinociceptive effects, and recent noninvasive approaches, termed transcutaneous-vagus nerve stimulation (t-VNS), have utilized stimulation of the auricular branch of the vagus nerve in the ear. - [Clinical Effectiveness of Percutaneous Auricular Vagus Nerve Stimulation in Chronic Back Pain Patients - A Single-Centre Retrospective Analysis](http://neurocareusa.com/clinical-effectiveness-of-percutaneous-auricular-vagus-nerve-stimulation-in-chronic-back-pain-patients-a-single-centre-retrospective-analysis/) - Chronic back pain is one of the biggest causes of disability today. The objective of this study was to evaluate the safety and effectiveness of percutaneous auricular Vagus Nerve Stimulation (pVNS) for chronic back pain patients in routine clinical practice. - [Non-Invasive Neuromodulation in Diabetic Peripheral Neuropathy: a meta-analysis (5484)](http://neurocareusa.com/non-invasive-neuromodulation-in-diabetic-peripheral-neuropathy-a-meta-analysis-5484/) - This systematic review aims to evaluate non-invasive neuromodulation (NINM) effects on Diabetic peripheral neuropathy (DPN) subjects measured by pain rating scales. - [Effect of deep tissue laser therapy treatment on peripheral neuropathic pain in older adults with type 2 diabetes: a pilot randomized clinical trial](http://neurocareusa.com/effect-of-deep-tissue-laser-therapy-treatment-on-peripheral-neuropathic-pain-in-older-adults-with-type-2-diabetes-a-pilot-randomized-clinical-trial/) - This study assessed the safety and efficacy of deep tissue laser therapy on the management of pain, functionality, systemic inflammation, and overall quality of life of older adults with painful diabetic peripheral neuropathy. - [Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge](http://neurocareusa.com/noninvasive-vagus-nerve-stimulation-alters-neural-response-and-physiological-autonomic-tone-to-noxious-thermal-challenge/) - The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation. - [Neurostimulation for Intractable Chronic Pain](http://neurocareusa.com/neurostimulation-for-intractable-chronic-pain/) - The field of neuromodulation has seen unprecedented growth over the course of the last decade with novel waveforms, hardware advancements, and novel chronic pain indications. We present here an updated review on spinal cord stimulation, dorsal root ganglion stimulation, and peripheral nerve stimulation. - [Non-invasive vagus nerve stimulation for acute treatment of high-frequency and chronic migraine: an open-label study](http://neurocareusa.com/non-invasive-vagus-nerve-stimulation-for-acute-treatment-of-high-frequency-and-chronic-migraine-an-open-label-study/) - The treatment of migraine headache is challenging given the lack of a standardized approach to care, unsatisfactory response rates, and medication overuse. - [COMPARATIVE EFFECTS OF THERAPEUTIC ULTRASOUND AND HIGH INTENSITY LASER THERAPY ON NEUROPATHIC PAIN, STRENGTH AND QUALITY OF LIFE IN DIABETIC FOOT](http://neurocareusa.com/comparative-effects-of-therapeutic-ultrasound-and-high-intensity-laser-therapy-on-neuropathic-pain-strength-and-quality-of-life-in-diabetic-foot/) - Diabetes mellitus is a major global health concern and a leading cause of morbidity, mortality, and long-term disability. - [Combined occipital and supraorbital neurostimulation for the treatment of chronic migraine headaches: initial experience](http://neurocareusa.com/combined-occipital-and-supraorbital-neurostimulation-for-the-treatment-of-chronic-migraine-headaches-initial-experience/) - A novel approach to the treatment of chronic migraine headaches based on neurostimulation of both occipital and supraorbital nerves was developed and reduced to clinical practice in a series of patients with headaches unresponsive to currently available therapies. - [Study of the outcome of patients undergoing pulsed radiofrequency for the treatment of Trigeminal Neuralgia; an observational study.](http://neurocareusa.com/study-of-the-outcome-of-patients-undergoing-pulsed-radiofrequency-for-the-treatment-of-trigeminal-neuralgia-an-observational-study/) - Trigeminal neuralgia is sudden unilateral severe, stabbing, recurrent episodes of pain in the distribution of one or more branches of the trigeminal nerve. - [The effect of photobiomodulation on chemotherapy-induced peripheral neuropathy: A randomized, sham-controlled clinical trial](http://neurocareusa.com/the-effect-of-photobiomodulation-on-chemotherapy-induced-peripheral-neuropathy-a-randomized-sham-controlled-clinical-trial/) - Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer therapy with few efficacious treatments. - [A review of vagus nerve stimulation as a therapeutic intervention](http://neurocareusa.com/a-review-of-vagus-nerve-stimulation-as-a-therapeutic-intervention/) - In this review, we provide an overview of the US Food and Drug Administration (FDA)-approved clinical uses of vagus nerve stimulation (VNS) as well as information about the ongoing studies and preclinical research to expand the use of VNS to additional applications. - [Influence of photobiomodulation on sensory symptoms, balance, and gait speed in chemotherapy-induced peripheral neuropathy](http://neurocareusa.com/influence-of-photobiomodulation-on-sensory-symptoms-balance-and-gait-speed-in-chemotherapy-induced-peripheral-neuropathy/) - Photobiomodulation (PBM) is a non-invasive therapy that uses low-level light in the visible and near-infrared spectrum to stimulate cellular processes, promoting tissue repair and reducing inflammation without causing thermal damage. - [Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis](http://neurocareusa.com/clinical-efficacy-of-auricular-vagus-nerve-stimulation-in-the-treatment-of-chronic-and-acute-pain-a-systematic-review-and-meta-analysis/) - Current guidelines for pain treatment recommend a personalized, multimodal and interdisciplinary approach as well as the use of a combination of drug and non-drug therapies. - [Quantum Biology and Healthcare: the Synergistic Bioeffect of Weak Electromagnetic Fields (EMFs) on Human Bodies](http://neurocareusa.com/quantum-biology-and-healthcare-the-synergistic-bioeffect-of-weak-electromagnetic-fields-emfs-on-human-bodies/) - Human bodies are constantly exposed to environmental electromagnetic sources. Both electric and magnetic fields are known to have an active role in altering biological activities. - [Dietary Intake of Magnesium or Calcium and Chemotherapy-Induced Peripheral Neuropathy in Colorectal Cancer Patients](http://neurocareusa.com/dietary-intake-of-magnesium-or-calcium-and-chemotherapy-induced-peripheral-neuropathy-in-colorectal-cancer-patients/) - Chemotherapy-induced peripheral neuropathy (CIPN) is a common and severe side-effect in colorectal cancer (CRC) patients. - [Adaptive Autonomic and Neuroplastic Control in Diabetic Neuropathy: A Narrative Review](http://neurocareusa.com/adaptive-autonomic-and-neuroplastic-control-in-diabetic-neuropathy-a-narrative-review/) - Type 2 diabetes mellitus (T2DM) is a worldwide socioeconomic burden, and is accompanied by a variety of metabolic disorders, as well as nerve dysfunction referred to as diabetic neuropathy (DN). - [Vitamin E for the Prevention of Chemotherapy-Induced Peripheral Neuropathy: A meta-Analysis](http://neurocareusa.com/vitamin-e-for-the-prevention-of-chemotherapy-induced-peripheral-neuropathy-a-meta-analysis/) - Vitamin E has been increasingly used to prevent chemotherapy-induced peripheral neuropathy (CIPN) in recent years. However, it is still unclear whether vitamin E can effectively prevent CIPN. - [Evaluation of the Safety and Efficacy of N-acetylcysteine in the Prevention of Paclitaxel-induced Peripheral Neuropathy: A Randomized, Double-blind, and Placebo-controlled Trial](http://neurocareusa.com/evaluation-of-the-safety-and-efficacy-of-n-acetylcysteine-in-the-prevention-of-paclitaxel-induced-peripheral-neuropathy-a-randomized-double-blind-and-placebo-controlled-trial/) - Paclitaxel-induced peripheral neuropathy (PIPN) is a disabling condition that leads to discontinuation or dose reduction of chemotherapy and reduces the patient’s quality of life (QOL). We investigated the effect of N-acetylcysteine (NAC) in preventing PIPN. - [Can an electrical pulsed radio frequency device relieve pain and improve function in patients with pedal diabetic neuropathy? A single blind randomized placebo-controlled trial.](http://neurocareusa.com/can-an-electrical-pulsed-radio-frequency-device-relieve-pain-and-improve-function-in-patients-with-pedal-diabetic-neuropathy-a-single-blind-randomized-placebo-controlled-trial/) - Can an electrical pulsed radio frequency device relieve pain and improve function in patients with pedal diabetic neuropathy? A single blind randomized placebo-controlled trial. - [The potential positive effects of coenzyme Q10 on the regeneration of peripheral nerve injury](http://neurocareusa.com/the-potential-positive-effects-of-coenzyme-q10-on-the-regeneration-of-peripheral-nerve-injury/) - Peripheral nerve injuries (PNIs) constitute a significant concern as they predominantly affect young and productive age groups of the population, causing social and economic pressure on patients. - [Curcumin as a promising therapeutic agent for diabetic neuropathy: from molecular mechanisms to functional recovery](http://neurocareusa.com/curcumin-as-a-promising-therapeutic-agent-for-diabetic-neuropathy-from-molecular-mechanisms-to-functional-recovery/) - Diabetes mellitus is an endocrine disorder characterized by prolonged hyperglycemia. It results from either insulin deficiency (type 1 diabetes mellitus, T1DM) or insulin resistance (type 2 diabetes mellitus, T2DM). - [Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes](http://neurocareusa.com/serum-lipidomic-determinants-of-human-diabetic-neuropathy-in-type-2-diabetes/) - The serum lipidomic profile associated with neuropathy in type 2 diabetes is not well understood. - [Clinical effectiveness of low-level laser treatment on peripheral somatosensory neuropathy](http://neurocareusa.com/clinical-effectiveness-of-low-level-laser-treatment-on-peripheral-somatosensory-neuropathy/) - Peripheral sensory neuropathy treatment is one of the common treatment problems and causes morbidity and mortality in people suffering from that. - [Perineural Platelet-Rich Plasma for Diabetic Neuropathic Pain, Could It Make a Difference?](http://neurocareusa.com/perineural-platelet-rich-plasma-for-diabetic-neuropathic-pain-could-it-make-a-difference/) - To evaluate the clinical effect of perineural platelet-rich plasma (PRP) injection for pain and numbness alleviation in diabetic peripheral neuropathy (DPN). - [Neuromodulation for Peripheral Nerve Regeneration: Systematic Review of Mechanisms and In Vivo Highlights](http://neurocareusa.com/neuromodulation-for-peripheral-nerve-regeneration-systematic-review-of-mechanisms-and-in-vivo-highlights/) - While denervation can occur with aging, peripheral nerve injuries are debilitating and often leads to a loss of function and neuropathic pain. Although injured peripheral nerves can regenerate and reinnervate their targets, this process is slow and directionless. - [Efficacy of Perineural Hypertonic Saline Injection Versus Acupoints of Foot in the Management of Diabetic Neuropathy: a Multicenter, Double-Blinded Randomized Controlled Trial](http://neurocareusa.com/efficacy-of-perineural-hypertonic-saline-injection-versus-acupoints-of-foot-in-the-management-of-diabetic-neuropathy-a-multicenter-double-blinded-randomized-controlled-trial/) - Painful diabetic polyneuropathy is one of the most common disabling problems worldwide. We aimed to determine if a perineural injection of hypertonic saline compared with foot acupoints decreased the neuropathic pain score in patients with diabetes. - [Percutaneous Peripheral Nerve Stimulation in Chemotherapy-Induced Neuropathy: A Case Report](http://neurocareusa.com/percutaneous-peripheral-nerve-stimulation-in-chemotherapy-induced-neuropathy-a-case-report/) - Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and limiting complication of oncological treatment, particularly in patients receiving oxaliplatin. - [The effect of perineural injection therapy on neuropathic pain: a retrospective study](http://neurocareusa.com/the-effect-of-perineural-injection-therapy-on-neuropathic-pain-a-retrospective-study/) - Among the various pain-related diseases that can be encountered at the clinic, there is a neuropathic pain that is difficult to treat. - [Neuroprotective Effects of Molecular Hydrogen: A Critical Review](http://neurocareusa.com/neuroprotective-effects-of-molecular-hydrogen-a-critical-review/) - Molecular hydrogen (H2) is a physiologically inert gas. However, during the last 10 years, increasing evidence has revealed its biological functions under pathological conditions. - [Clinical Effects of Hydrogen Administration: From Animal and Human Diseases to Exercise Medicine](http://neurocareusa.com/clinical-effects-of-hydrogen-administration-from-animal-and-human-diseases-to-exercise-medicine/) - Here we review the literature on the effects of molecular hydrogen (H2) on normal human subjects and patients with a variety of diagnoses, such as metabolic, rheumatic, cardiovascular and neurodegenerative and other diseases, infections and physical and radiation damage as well as effects on aging and exercise. - [Efficacy of transauricular vagus nerve stimulation for the treatment of chemotherapy-induced painful peripheral neuropathy: a randomized controlled exploratory study](http://neurocareusa.com/efficacy-of-transauricular-vagus-nerve-stimulation-for-the-treatment-of-chemotherapy-induced-painful-peripheral-neuropathy-a-randomized-controlled-exploratory-study/) - Chemotherapy-induced painful peripheral neuropathy (CIPN) is a common adverse event in cancer patients, and there is still a lack of effective treatment. Transauricular vagal nerve stimulation (taVNS) is a minimally invasive treatment, but there are few reports regarding its efficacy for CIPN. - [Evaluating the efficacy of photobiomodulation therapy in the management of chemotherapy-induced peripheral neuropathy: a pilot trial (NEUROLIGHT trial)](http://neurocareusa.com/evaluating-the-efficacy-of-photobiomodulation-therapy-in-the-management-of-chemotherapy-induced-peripheral-neuropathy-a-pilot-trial-neurolight-trial/) - Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy that hinders the patient’s health-related quality of life (HRQL). - [Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles -](http://neurocareusa.com/beneficial-biological-effects-and-the-underlying-mechanisms-of-molecular-hydrogen-comprehensive-review-of-321-original-articles/) - Therapeutic effects of molecular hydrogen for a wide range of disease models and human diseases have been investigated since 2007. A total of 321 original articles have been published from 2007 to June 2015. - [Various gases for the treatment of neuropathic pain: mechanisms, current status, and future perspectives](http://neurocareusa.com/various-gases-for-the-treatment-of-neuropathic-pain-mechanisms-current-status-and-future-perspectives/) - In recent years, medical gas therapy has emerged as a promising approach for treating neuropathic pain. This review article aimed to investigate the therapeutic effects of medical gas therapy on neuropathic pain and its underlying mechanisms, thereby providing a theoretical foundation for clinical practice. - [Effect of High-Power Laser Therapy on Modified Total Neuropathy Score in Patients with Chemotherapy Induced Peripheral Neuropathy](http://neurocareusa.com/effect-of-high-power-laser-therapy-on-modified-total-neuropathy-score-in-patients-with-chemotherapy-induced-peripheral-neuropathy/) - Peripheral neuropathy is a common problem among cancer patients receiving chemotherapy. - [Omega-3 Polyunsaturated Fatty Acids (PUFAs) and Diabetic Peripheral Neuropathy: A Pre-Clinical Study Examining the Effect of Omega-3 PUFAs from Fish Oil, Krill Oil, Algae or Pharmaceutical-Derived Ethyl Esters Using Type 2 Diabetic Rats](http://neurocareusa.com/omega-3-polyunsaturated-fatty-acids-pufas-and-diabetic-peripheral-neuropathy-a-pre-clinical-study-examining-the-effect-of-omega-3-pufas-from-fish-oil-krill-oil-algae-or-pharmaceutical-derived-eth/) - We have previously reported that omega-3 polyunsaturated fatty acids (PUFAs) derived from fish oil (FO) is an effective treatment for type 1 and type 2 diabetes neural and vascular complications. - [Hyperbaric oxygen treatment attenuates neuropathic pain by elevating autophagy flux via inhibiting mTOR pathway](http://neurocareusa.com/hyperbaric-oxygen-treatment-attenuates-neuropathic-pain-by-elevating-autophagy-flux-via-inhibiting-mtor-pathway/) - Peripheral neuropathic pain is a complex disease, and treated based on underlying diseases. Emerging evidences suggest that hyperbaric oxygen alleviates neuropathic pain. However, its cellular and molecular mechanism on pain relief is unknown. - [Efficacy and safety of hyperbaric oxygen therapy for diabetes peripheral neuropathy: A systematic review and meta-analysis](http://neurocareusa.com/efficacy-and-safety-of-hyperbaric-oxygen-therapy-for-diabetes-peripheral-neuropathy-a-systematic-review-and-meta-analysis/) - Diabetes peripheral neuropathy (DPN) is mainly treated with diabetes as a whole, and there is no targeted treatment. Some studies have reported that adjuvant hyperbaric oxygen therapy (HBOT) for DPN has achieved a good effect, our study aimed to evaluate the clinical efficacy and safety of HBOT for DPN and provide reference for the clinic by using a systematic review and meta-analysis. - [Ameliorative Effects Of N-Acetylcysteine As Adjunct Therapy On Symptoms Of Painful Diabetic Neuropathy](http://neurocareusa.com/ameliorative-effects-of-n-acetylcysteine-as-adjunct-therapy-on-symptoms-of-painful-diabetic-neuropathy/) - Painful diabetic neuropathy (PDN) is a variant of diabetic peripheral neuropathy which is highly prevalent and distressing in diabetic patients. Despite its high burden, the optimal treatment of PDN has remained a clinical challenge. - [Long-Term Effects of Ozone Treatment in Patients with Persistent Numbness and Tingling Secondary to Chemotherapy-Induced Peripheral Neuropathy. A Retrospective Study](http://neurocareusa.com/long-term-effects-of-ozone-treatment-in-patients-with-persistent-numbness-and-tingling-secondary-to-chemotherapy-induced-peripheral-neuropathy-a-retrospective-study/) - Numbness and tingling secondary to chemotherapy-induced peripheral neuropathy (CIPN) are frequent side effects that limit chemotherapy treatment and quality of life. Successful treatments for CIPN are limited. - [Effect of high-dose N-acetyl cysteine on the clinical outcome of patients with diabetic peripheral neuropathy: a randomized controlled study](http://neurocareusa.com/effect-of-high-dose-n-acetyl-cysteine-on-the-clinical-outcome-of-patients-with-diabetic-peripheral-neuropathy-a-randomized-controlled-study/) - Diabetic peripheral neuropathy (DPN) is a vastly common and bothersome disorder with a clinically challenging course of treatment affecting patients with diabetes. This study aimed to evaluate the efficacy and safety of high dose oral N-acetyl cysteine (NAC) as adjuvant therapy on clinical outcome of DPN. - [Diabetic peripheral neuropathy: Role of nitric oxide](http://neurocareusa.com/diabetic-peripheral-neuropathy-role-of-nitric-oxide/) - Diabetic peripheral neuropathy (DPN) is one of the most prevalent long-term complications in type 1 (T1DM) and type 2 (T2DM) diabetes mellitus and is characterized by structural (microangiopathy, axonal atrophy, impaired myelination, and disrupted Schwann cell-axon interactions) and functional (impaired axonal transport and sensory and motor disorders) changes in neurons. - [Therapeutic roles of coenzyme Q10 in peripheral nerve injury-induced neurosensory disturbances: Mechanistic insights from injury to recovery](http://neurocareusa.com/therapeutic-roles-of-coenzyme-q10-in-peripheral-nerve-injury-induced-neurosensory-disturbances-mechanistic-insights-from-injury-to-recovery/) - Peripheral nerve injuries (PNIs) are prevalent conditions mainly resulting from systemic causes, including autoimmune diseases and diabetes mellitus, or local causes, for example, chemical injury and perioperative nerve injury, which can cause a varying level of neurosensory disturbances (NSDs). - [The Therapeutic Potential of Antioxidants in Chemotherapy-Induced Peripheral Neuropathy: Evidence from Preclinical and Clinical Studies](http://neurocareusa.com/the-therapeutic-potential-of-antioxidants-in-chemotherapy-induced-peripheral-neuropathy-evidence-from-preclinical-and-clinical-studies/) - As cancer therapies advance and patient survival improves, there has been growing concern about the long-term adverse effects that patients may experience following treatment, and concerns have been raised about such persistent, progressive, and often irreversible adverse effects. ## Pages - [Home](http://neurocareusa.com/) - INTEGRATIVE NON-SURGICAL NEUROMUSCULOSKELETAL CARE Natural, effective pain solutions to help you restore to your peak performance We use a personalized, comprehensive approach of researched backed – opioid free – advanced therapies for rapid and effective pain relief for athletes, surgical or injury recovery, neuropathy and everyone who suffers from nerve or joint pain.It’s time to - [Nerve Pain](http://neurocareusa.com/what-we-treat/nerve-joint-pain/) - About Neurogenic Pain Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the - [Regenerative Injection Therapy (RIT)](http://neurocareusa.com/how-we-treat/regenerative-injection-therapy-rit/) - About Regenerative Injection Therapy (RIT) RIT treats and aims to correct acute and chronic musculoskeletal pain by injecting sterile, natural nutraceutical agents into joint spaces, scars, and muscles and around nerves, fascia, ligaments, and tendons. Multiple injections are performed in the effective target region during each RIT treatment. How RIT Works? The sterile, natural nutraceutical - [Cranial cervical Therapy (CCT)](http://neurocareusa.com/how-we-treat/cranial-cervical-therapy-cct/) - About Cranialcervical Therapy (CCT) CCT targets root causes and focuses on precise, gentle neuromyofunctional correction of the entire cranialfacial-cervical-spinal complex, through non-surgical techniques. How CCT Works? Micro misalignments in the cranialfacial-cervical-spinal complex from trauma, poor posture or lifestyle habits cause neuromyofunctional dysfunction and development issues throughout the entire body. Micro misalignments are mapped out through - [Robotic Spinal Decompression Therapy (RSDT)](http://neurocareusa.com/how-we-treat/robotic-spinal-decompression-therapy-rsdt/) - About Robotic Spinal Decompression Therapy (RSDT) RSDT uses computerized, automated spinal decompression technology to gentle maneuver the spine to create increased mobility and intradiscal pressure to heal spinal disorders without surgery, anesthesia, or downtime. It is FDA-cleared technology as an alternative to restoring spinal health naturally. How RSDT Works? A patient lies on a robotic, motorized - [Personalized Nutraceutical Therapy (PNT)](http://neurocareusa.com/how-we-treat/personalized-nutraceutical-therapy-pnt/) - About Personalized Nutraceutical Therapy PNT integrates an individual’s unique diagnostic data such as: biochemistry, genetics, microbiome and complete health profile to tailor a specific meal plan and clinical potency bioactive compounds of professional grade vitamins, minerals, botanicals, and other nutraceuticals for targeted therapeutic outcomes and overall health, general wellness and longevity. PNT is usually combined - [Lymphatic Resonance Modulation Therapy (LRMT)](http://neurocareusa.com/how-we-treat/lymphatic-resonance-modulation-therapy-lrmt/) - About Lymphatic Resonance Modulation Therapy (LRMT) LRMT is a non-invasive lymphatic drainage and detoxification wellness treatment using photobiomodulation, low intensity pulsed frequencies, and oxygen to clear chronic lymph stagnation without cytotoxicity or creating a healing crisis. Key Benefits of LRMT Lymph Detox: Rapidly resolves blockages for edema reduction. Pain Relief: Gently eases lymph congestion by enhancing - [High Intensity Laser Therapy](http://neurocareusa.com/how-we-treat/high-intensity-laser-therapy-hilt/) - About High Intensity Laser Therapy (HILT) HILT employs powerful infrared lasers to deliver concentrated photon energy deep into tissues up to 12 cm / 4.72 in deep, far surpassing low-level laser or light therapy (LLLT) in power density. Unlike LLLT’s subtle biostimulation, HILT combines photobiomodulation biostimulation with mild photothermal effects for a rapid therapeutic impact - [Enhanced Oxygen Therapy (EOT)](http://neurocareusa.com/how-we-treat/enhanced-oxygen-therapy-eot/) - About Enhanced Oxygen Therapy (EOT) EOT is a non-invasive wellness protocol to super saturate blood plasma and tissues with oxygen, bypassing red blood cell limitations to reverse hypoxia-related conditions. Key Benefits of EOT Energy & Recovery: Increase mitochondrial efficiency, reduces fatigue, and increases exercise recovery by 20-30%. Detox & Immunity: Flushes toxins, spikes white blood - [High Intensity Pulsed Electromagnetic Therapy (HIPEMF)](http://neurocareusa.com/how-we-treat/high-intensity-pulsed-electromagnetic-therapy-hipemf/) - About High Intensity Pulsed Electromagnetic Therapy (HIPEMF) HIPEMF delivers powerful, short bursts of electromagnetic fields, up to several Tesla, through specific applicators to penetrate deep tissues, stimulating cellular repair non-invasively for musculoskeletal conditions, neuropathy and urinary incontinence. Unlike low-intensity PEMF, HI-PEMF uses high peak amplitudes with low repetition frequencies, inducing strong electric currents via Faraday’s law - [Focused Shockwave Therapy (FSWT)](http://neurocareusa.com/how-we-treat/focused-shockwave-therapy-fswt/) - About Focused Shockwave Therapy (FSWT) Focused shockwave therapy (FSWT) is a non-invasive treatment delivering high-energy acoustic waves precisely to deep tissues, unlike radial shockwave therapy that largely disperses energy only superficially. FSWT treats tendinopathies (rotator cuff, Achilles, tennis elbow, etc.), plantar fasciitis, myofascial pain, bursitis, stress fracturs, sexual dysfunction, and wounds. The generated focused acoustic - [Neuromuscular Re-education (NMR)](http://neurocareusa.com/how-we-treat/neuromuscular-re-education-nmr/) - About Neuromuscular Reeducation (NMR) NMR with adaptive, automated training retrains dysfunctional brain-muscle communication using AI-driving technology that instantly adjusts load to muscle capacity across the full range of motion. This restores optimal firing patterns and losses from injury, surgery, or chronic pain, preventing compensatory movements that perpetuate dysfunction. How NMR Works? Proprioceptive neuromuscular facilitation principles - [Photobiomodulation Therapy (PBMT)](http://neurocareusa.com/how-we-treat/photobiomodulation-therapy-pbmt/) - About Photobiomodulation Therapy (PBMT) PBMT, formerly known as low-level laser or light therapy (LLLT), is a form of light therapy that utilizes non-ionizing forms of light sources, including LASERS, LEDs, and broad-band light, in the visible and infrared spectrum. It is a non-thermal process involving endogenous chromophores eliciting photophysical (i.e. linear and non-linear) and photochemical - [Neuromodulation Therapy](http://neurocareusa.com/how-we-treat/neuromodulation-therapy-nmt/) - About Neuromodulation Therapy (NMT) NMT is an FDA-cleared, non-invasive treatment to treat neuropathic pain and nerve dysfunction. It combines low frequency nerve mapping with patented high frequency pulsed waveforms, creating a healing electromagnetic field that targets nerves transdermally without needles or surgery. How NMT Works? The technology precisely pinpoints damaged or injured nerves through low - [Long Haul COVID](http://neurocareusa.com/what-we-treat/intractable-pain/long-haul-covid/) - About Long Covid Long COVID, formally known as Post Acute Sequelae of SARS CoV 2 Infection (PASC), refers to a range of new, returning, or ongoing symptoms that persist for at least three months after the initial SARS CoV 2 infection, in people who were not hospitalized or who have clinically recovered from acute COVID - [Complex Regional Pain Syndrome](http://neurocareusa.com/what-we-treat/intractable-pain/complex-regional-pain-syndrome/) - About Complex Regional Pain Syndrome (CRPS) Complex Regional Pain Syndrome (CRPS) is rare with a prevalence of 5–26 per 100,000 people annually; women 3–4x more affected; peak age 40–60, with up to 200,000 U.S. cases per year. CRPS is a chronic neurogenic pain disorder causing severe, disproportionate pain after minor injury or trauma, often in - [Intractable Pain](http://neurocareusa.com/what-we-treat/intractable-pain/) - About Intractable Pain Syndrome (IPS) IPS is a severe, constant, and debilitating form of chronic pain that resists all standard medical, surgical, pharmacological, or interventional treatments. Unlike typical chronic pain, it dominates every conscious moment, often rendering people bed- or house-bound or severe limitations, with profound physical and psychological debilitation. It triggers systemic biologic effects, - [Wrist & Hand Pain](http://neurocareusa.com/what-we-treat/joint-pain/wrist-hand-pain/) - About Wrist & Hand Pain Wrist and hand pain are common, with population based data suggesting that about 10% of adults report wrist and hand pain in the prior week, and roughly 19% report pain sometime within the past year. In manual labor and sports related groups, prevalence can be substantially higher, reaching about 24% - [Foot & Toe Pain](http://neurocareusa.com/what-we-treat/joint-pain/foot-toe-pain/) - About Foot & Toe Pain Foot and toe pain is highly prevalent, with survey data suggesting that about 17–24% of adults experience foot and toe pain at any given time, and up to 80% report having had foot and toe pain at some point in their lives. Large scale surveys also indicate that more than - [Shoulder Pain](http://neurocareusa.com/what-we-treat/joint-pain/shoulder-pain/) - About Shoulder Pain Shoulder pain is one of the most common musculoskeletal complaints. Population based studies report 1 month prevalence of about 15–30% of adults and lifetime prevalence estimates as high as roughly 30–67%, making it second only to low back pain in frequency, and women are slightly more affected than men. Symptoms Common symptoms - [Neck Pain](http://neurocareusa.com/what-we-treat/joint-pain/neck-pain/) - About Neck Pain Neck pain is very common, with roughly one third of adults experiencing neck symptoms in any given year; estimates of annual prevalence range from about 30% to 50% in the general adult population, and women report it more often than men. About 20–40% of those with neck pain go on to have - [Knee Pain](http://neurocareusa.com/what-we-treat/joint-pain/knee-pain/) - About Knee Pain Knee pain is one of the most common musculoskeletal complaints, affecting a substantial proportion of adults at any given time. National surveys indicate that about 16–20% of U.S. adults report knee pain in a 1 month window, with prevalence rising sharply with age and exceeding 25% among adults over age 45. In - [Hip Pain](http://neurocareusa.com/what-we-treat/joint-pain/hip-pain/) - About Hip Pain Hip pain affects about 10% for chronic hip pain in the general adult population, rising with age. Studies of older adults (60+) report that roughly 14% report significant hip pain on most days over a 6 week period, and hip osteoarthritis alone affects nearly 5% of adults aged 50+ with symptomatic disease - [Elbow Pain](http://neurocareusa.com/what-we-treat/joint-pain/elbow-pain/) - About Elbow Pain Elbow pain is a common musculoskeletal complaint, with lateral epicondylitis (tennis elbow) estimated to affect roughly 1–3% of adults and medial epicondylitis (golfer’s elbow) to affect less than 1% annually, accounting for most elbow related pain, especially among adults aged 40–60. Symptoms Common symptoms are aching or burning pain localized to the - [Back Pain](http://neurocareusa.com/what-we-treat/joint-pain/back-pain/) - About Back Pain Back pain affects 24.3% of adults with chronic pain in 2023 (up from 20.4% in 2019), and 8.5% with high-impact chronic pain that limits life or work activities. About 39% reported back pain in the past three months per 2019 CDC data, with 16 million adults (8%) experiencing chronic cases—rising to 45.6% - [Achilles & Ankle Pain](http://neurocareusa.com/what-we-treat/joint-pain/achilles-ankle-pain/) - About Achilles & Ankle Pain Achilles and ankle pain affects 6-24% of the general population lifetime, rising to 24% in athletes and 36-52% in runners, with general prevalence around 2-6% annually. Ankle sprains, a common cause of such pain, impact 2 per 1,000 people yearly, often leading to chronic issues Symptoms Pain manifests as stiffness, - [Joint Pain](http://neurocareusa.com/what-we-treat/joint-pain/) - About Joint Pain Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also - [Arthritis Pain](http://neurocareusa.com/what-we-treat/joint-pain/arthritis-pain/) - About Osteoarthritis (OA) Pain Osteoarthritis (OA) prevalence is high – about 10% of people over 60 years of age have symptomatic OA, rising to 30%+ by age 80, with the knees, then hips, hands, and spine most commonly affected. OA pain arises from ligament instability and cartilage breakdown, triggering multiple mechanisms: periosteal irritation from osteophytes, - [Nociceptive Pain](http://neurocareusa.com/what-we-treat/joint-pain/nociceptive-pain/) - About Nociceptive Pain Nociceptive pain is the body’s normal protective response to actual or potential tissue damage, triggered when specialized sensory nerve endings called nociceptors detect harmful mechanical, thermal, or chemical stimuli. Unlike neurogenic pain from nervous system dysfunction, nociceptive pain serves an adaptive warning function—think stubbing your toe, touching a hot stove, or spraining - [Neuropathy Symptoms](http://neurocareusa.com/what-we-treat/neuropathy-symptoms/) - About this service Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the - [Tarsal Tunnel Syndrome](http://neurocareusa.com/what-we-treat/tarsal-tunnel-syndrome/) - About Tarsal Tunnel Syndrome (TTS) TTS is rare, with unknown exact population incidence (under 1% of foot/ankle complaints); higher in women, athletes (runners), ages 30-50, diabetics, or post-trauma; 20-40% idiopathic. TTS is compression of the posterior tibial nerve or its branches (medial/lateral plantar nerves) within the tarsal tunnel behind the medial ankle malleolus, beneath the - [Cubital Tunnel Syndrome](http://neurocareusa.com/what-we-treat/cubital-tunnel-syndrome/) - About Cubital Tunnel Syndrome (CuTS) CuTS is is the second most common upper extremity compression neuropathy (after CTS), with incidence ~25 per 100,000 annually—1/13th of CTS; twice as common in men, left side > right, peaks ages 40-60. CuTS involves compression of the ulnar nerve at the elbow within the cubital tunnel (under Osborne’s ligament), - [Carpal Tunnel Syndrome](http://neurocareusa.com/what-we-treat/carpal-tunnel-syndrome/) - About Carpal Tunnel Syndrome (CTS) CTS affects 3-6% of adults with a higher propensity in women 45 to 60 years old that have a history of repetitive work. True CTS is compression of the median nerve within the carpal tunnel at the wrist, causing hand/wrist pain, while pseudo-carpal tunnel syndrome (PCTS) mimics CTS symptoms but - [Pudendal Neuralgia](http://neurocareusa.com/what-we-treat/pudendal-neuralgia/) - About Pudendal Neuralgia (PN) PN affects women more than men and often in ages 40 to 60 years old; seen in 1-20% of chronic pelvic pain cases, with a higher incident among cyclists or post-childbirth. It is a chronic neurogenic pain condition caused by irritation, compression, or damage to the pudendal nerve, which supplies sensation - [Occipital Neuralgia](http://neurocareusa.com/what-we-treat/occipital-neuralgia/) - About Occipital Neuralgia Occipital Neuralgia (ON) affects 3.2/100,000 people annually and is prevalent in women greater than men and is differentiated from a facet-mediated cervicogenic headache. ON is a headache disorder caused by irritation, compression, or injury to the occipital nerves (greater, lesser, third), which run from the upper cervical spine (C2-C3 roots) through the - [Migraine Headaches](http://neurocareusa.com/what-we-treat/migraine-headaches/) - About Migraine Headaches Migraine Headaches (MH) are prevalent in 15% of the population affecting women 3:1 compared to men. MH are a neurological disorder featuring recurrent episodes of moderate-to-severe throbbing head pain, typically unilateral (one-sided) but sometimes bilateral, lasting 4-72 hours if untreated, with a 60% moderate to severe impairment during attacks. Unlike tension headaches - [Traumatic Brain Injury](http://neurocareusa.com/what-we-treat/traumatic-brain-injury/) - About Traumatic Brain Injuries (TBIs) TBIs affects 2.8 million US people per year with the majority (70%) of cases being mild. TBIs occur when external mechanical force causes brain dysfunction, ranging from mild concussion to severe diffuse axonal injury. TBIs disrupt neuronal integrity, neurotransmitter balance, and cerebral blood flow, classified by Glasgow Coma Scale (GCS - [Trigeminal Neuralgia](http://neurocareusa.com/what-we-treat/trigeminal-neuralgia/) - About Trigeminal Neuralgia (TM) TN affects about 4-13 people per 100,000 annually, with lifetime prevalence around 0.16%-0.3%; women are 1.5-3 times more likely than men, and incidence rises sharply after age 50, reaching 23-45 per 100,000 in those over 80. Trigeminal neuralgia (TN), often called “tic douloureux,” is a chronic pain disorder affecting the trigeminal - [Meralgia Parasthesia](http://neurocareusa.com/what-we-treat/meralgia-parasthesia/) - About Meralgia Paresthesia (MP) MP is uncommon, with no precise population-wide rates established in major studies from the provided data; it affects adults primarily (ages 30-60), more often in obese individuals or during pregnancy, but exact incidence remains underreported. (MP), also known as lateral femoral cutaneous nerve entrapment, is a mononeuropathy causing pain, tingling, numbness, - [Sciatica](http://neurocareusa.com/what-we-treat/sciatica/) - About Sciatica Sciatica affects 10-40% of adults lifetime, with annual incidence around 1-5%; risk rises with age (peak 40-50s), obesity, sedentary jobs, pregnancy, and manual labor, impacting millions yearly. Sciatica is pain radiating along the sciatic nerve path, the body’s largest nerve, from the lower back through the hips, buttocks, and down one leg, often - [Piriformis Syndrome](http://neurocareusa.com/what-we-treat/piriformis-syndrome/) - About Piriformis Syndrome (PS) PS usually affects one side and more common in middle-aged adults and in females. It is a painful musculoskeletal condition in which the piriformis muscle in the deep buttock tightens, spasms, or becomes inflamed and compresses the sciatic nerve, producing “false sciatica.” This leads to buttock pain that can radiate down - [Neurogenic Pain](http://neurocareusa.com/what-we-treat/neurogenic-pain/) - About Neurogenic Pain Neurogenic pain, also called neuropathic pain, arises from damage or dysfunction within the nervous system itself, rather than tissue injury. It encompasses neuropathic pain (peripheral nerve lesions), central pain (brain/spinal cord damage), and deafferentation pain (sensory loss), where nerves generate aberrant signals spontaneously. Types & Characteristics: Peripheral Neurogenic Pain Common forms include - [WHAT WE TREAT](http://neurocareusa.com/what-we-treat/) - Nerve Pain Get rapid relief from nerve pain such as, sciatica, carpal tunnel, migraines, etc. Learn More Neuropathy Symptoms Get rapid relief from neuropathy symptoms such as, burning, coldness, numbness, muscle weakness, etc. Learn More Joint Pain Get rapid relief from acute or chronic joint pain from osteoarthritis, bursitis, tendonitis, an accident or injury, etc. - [Clinics](http://neurocareusa.com/find-a-provider/) - Find a Provider oklahoma NeuroCare USA7633 East 63rd Place STE 300 Tulsa, Oklahoma 74133 NeuroCare Bixby5085 East 151st Street STE B Bixby, Oklahoma 74008 missouri NeuroCare St. Louis13302 Manchester Road Des Peres, Missouri 63131 NeuroCare Cape Girardeau1424 Kurre Lane Cape Girardeau, Missouri 63701 - [Pricing & Payment](http://neurocareusa.com/pricing-payment/) - Lorem ipsum dolor sit amet, consectetur adipiscing elit. 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View Service - [Regenerative Injection Therapy](http://neurocareusa.com/how-we-treat/regenerative-injection-therapy/) - Nerve & Joint Pain Nerve & Joint Pain We use a personalized comprehensive approach of proven, opioid free, advanced therapies for rapid pain relief and optimal healing & recovery About this service Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the - [Shockwave Therapy](http://neurocareusa.com/how-we-treat/shockwave-therapy/) - Nerve & Joint Pain Nerve & Joint Pain We use a personalized comprehensive approach of proven, opioid free, advanced therapies for rapid pain relief and optimal healing & recovery About this service Lorem Ipsum is simply dummy text of the printing and typesetting industry. 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